What is your preferred keyboard button layout for playing fangames?

[gamester]

Everyone who makes a game has to decide which buttons are going to be used to play it. For most MFGG games, the buttons typically include the following:

-Arrow keys
-Shift (do you want to turn on sticky keys?)
-Ctrl
-Alt
-Spacebar
-Letters - 'Z' , 'X' , 'C'

We are well beyond the point where if you don't like the control layout, you can change it using code, keyboard mapping apps, pc controllers, etc.

But since we are discussing the keyboard:

What is your preferred layout?
Do button actions (run, jump, start, pause, etc.) feel most natural in a particular layout?
Any layouts that you dislike?

(This post may or may not be valuable for the current generation of fangame creators)